5-Methyl-ethylone (5-methyl-bk-MDEA, 5ME) is an Amphetamine, Phenethylamine, and Cathinone drug class entactogen, stimulant and psychedelic drug. Ethylone, a novel designer drug, is structurally related to it. There is very little evidence on 5-methyl-pharmacological ethylone’s properties, metabolism, and toxicity.